T-regulatory cells in primary immune deficiencies.


PURPOSE OF REVIEW To summarize studies on the development and function of T-regulatory (TR) cells in primary immune deficiencies (PIDs). RECENT FINDINGS PIDs are associated with high rates of autoimmunity. TR cells, which are critical to the control of autoimmunity, appear involved in the pathogenesis of PID-related autoimmunity. A number of PIDs… (More)
DOI: 10.1097/ACI.0b013e32834cb8fa


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