T regulatory cells: aid or hindrance in the clearance of disease?

Abstract

CD4+ CD25+ T regulatory cells (Tregs) are classified as a subset of T cells whose role is the suppression and regulation of immune responses to self and non-self. Since their discovery in the early 1970s, the role of CD4+ CD25+ Tregs in both autoimmune and infectious disease has continued to expand. This review examines the recent advances on the role CD4… (More)
DOI: 10.1111/j.1582-4934.2007.00087.x

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