T-regulatory cell modulation: the future of cancer immunotherapy?

@article{Nizar2009TregulatoryCM,
  title={T-regulatory cell modulation: the future of cancer immunotherapy?},
  author={S. Mohamed Nizar and John P. Copier and Brendan J. Meyer and Mark D. Bodman-Smith and Christine Galustian and D Kumar and Angus George Dalgleish},
  journal={British Journal of Cancer},
  year={2009},
  volume={100},
  pages={1697 - 1703}
}
T-regulatory cells suppress anti-tumour immunity in cancer patients and in murine tumour models. Furthermore, their activity is likely to have an effect on the effectiveness of immunotherapeutic treatments for cancer. Here we describe the current status of developing clinical strategies for modulating Treg activity in cancer patients. 

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 55 references

: results and possible immune system - related mechanisms

C Lonnroth, M Andersson, +4 authors K Lundholm
2008
View 1 Excerpt

Ctla-4 blockade confers lymphocyte resistance to regulatory T-cells in advanced melanoma: surrogate marker of efficacy of tremelimumab?

Clinical cancer research : an official journal of the American Association for Cancer Research • 2008
View 1 Excerpt

Similar Papers

Loading similar papers…