T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats.

@article{Moalem2004TLP,
  title={T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats.},
  author={Gila Moalem and Kaiping Xu and L Yu},
  journal={Neuroscience},
  year={2004},
  volume={129 3},
  pages={767-77}
}
A catastrophic consequence of peripheral nerve injury is the development of abnormal, chronic neuropathic pain. The inflammatory response at the injury site is believed to contribute to the generation and maintenance of such persistent pain. However, the physiological significance and potential contribution of T cells to neuropathic pain remains unclear. Here we show that T cells infiltrate injured sciatic nerves following chronic constriction injury (CCI), but not uninjured nerves… CONTINUE READING
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