T lymphocytes from T. cruzi-infected mice alter heart contractility: participation of arachidonic acid metabolites.

Abstract

T lymphocytes from T. cruzi infected mice susceptible to the development of myocarditis altered the contractility of normal mouse atria in vitro. While lymphocytes obtained from normal mice had no effect, lymphocytes from T. cruzi-infected mice cultured with normal atria induced negative or positive inotropic effects depending upon the post-infection period… (More)

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