T-lymphocyte populations, cytokines and other growth factors in serum and urine of children with idiopathic nephrotic syndrome.

@article{Daniel1997TlymphocytePC,
  title={T-lymphocyte populations, cytokines and other growth factors in serum and urine of children with idiopathic nephrotic syndrome.},
  author={Volker Daniel and Y. Trautmann and Martin Konrad and Ahmet Nayir and Karl Schaerer},
  journal={Clinical nephrology},
  year={1997},
  volume={47 5},
  pages={289-97}
}
The T-cell defect present in the idiopathic nephrotic syndrome (INS) was investigated in 29 steroid-sensitive and 14 steroid-resistant children aged 2-19 years. Nine different lymphocyte subpopulations and 15 cytokines, receptors and other growth factors were measured in blood, and some also in urine. In steroid-sensitive patients we found a decreased ratio of helper/inducer cells (CD4+) versus suppressor/cytotoxic cells (CD8+) in relapse and remission, and an increased proportion of natural… CONTINUE READING

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