T-independent and T-dependent steps in the murine B cell response to antiimmunoglobulin

@article{Birkeland1987TindependentAT,
  title={T-independent and T-dependent steps in the murine B cell response to antiimmunoglobulin},
  author={Marian L. Birkeland and Laura R. Simpson and Peter C. Isakson and Ellen Pur{\'e}},
  journal={The Journal of Experimental Medicine},
  year={1987},
  volume={166},
  pages={506 - 519}
}
Sepharose-anti-Ig and purified populations of small, high-density B cells have been used to study the formation and function of B lymphoblasts. Sepharose-anti-Ig converts small, Ia-poor B cells with a high-buoyant density to large, Ia-rich, B blasts with a low-buoyant density. We find that this response proceeds efficiently in the absence of IL-4 (BSF-1) as… CONTINUE READING