T helper subsets in Sjögren's syndrome and IgG4-related dacryoadenitis and sialoadenitis: a critical review.

  title={T helper subsets in Sj{\"o}gren's syndrome and IgG4-related dacryoadenitis and sialoadenitis: a critical review.},
  author={Masafumi Moriyama and Akihiko Tanaka and Takashi Maehara and Sachiko Furukawa and Hitoshi Nakashima and Seiji Nakamura},
  journal={Journal of autoimmunity},
IgG4-related disease (IgG4-RD) is a systemic disease characterized by the elevation of serum IgG4 and infiltration of IgG4-positive plasma cells in multiple target organs, including the pancreas, kidney, biliary tract and salivary glands. In contrast, Mikulicz's disease (MD) has been considered a subtype of Sjögren's syndrome (SS) based on histopathological similarities. However, it is now recognized that MD is an IgG4-RD distinguishable from SS and called as IgG4-related dacryoadenitis and… CONTINUE READING


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