T-helper cell responses to HIV envelope peptides in cord blood: protection against intrapartum and breast-feeding transmission.

@article{Kuhn2001ThelperCR,
  title={T-helper cell responses to HIV envelope peptides in cord blood: protection against intrapartum and breast-feeding transmission.},
  author={Louise Kuhn and Anna Coutsoudis and Dhayendre Moodley and Daria Lucia Trabattoni and Nolwandle Mngqundaniso and Gene M. Shearer and Mario Clerici and Hoosen Mahomed Coovadia and Zena A. Stein},
  journal={AIDS},
  year={2001},
  volume={15 1},
  pages={1-9}
}
BACKGROUND Acquired HIV-specific cell-mediated immune responses have been observed in exposed-uninfected individuals, and it has been inferred, but not demonstrated, that these responses constitute a part of natural protective immunity to HIV. This inference was tested prospectively in the natural exposure setting of maternal-infant HIV transmission in a predominantly breast-fed population. METHODS Cord blood from infants of HIV-seropositive women in Durban, South Africa, were tested for in… CONTINUE READING

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