T helper cell‑related cytokine gene polymorphisms and vitamin D pathway gene polymorphisms as predictors of survival probability in patients on renal replacement therapy.

@article{widerska2015THC,
  title={T helper cell‑related cytokine gene polymorphisms and vitamin D pathway gene polymorphisms as predictors of survival probability in patients on renal replacement therapy.},
  author={Monika K Świderska and Adrianna Mostowska and Alicja E. Grzegorzewska},
  journal={Polskie Archiwum Medycyny Wewnetrznej},
  year={2015},
  volume={125 7-8},
  pages={
          511-20
        }
}
INTRODUCTION Negative outcomes in patients on renal replacement therapy (RRT) may have a source in T helper (Th)-cell imbalance or vitamin D deficiency. OBJECTIVES We examined the association of genes encoding cytokines related to Th1 and Th2 cells and vitamin D pathway genes with survival probability of patients on RRT. PATIENTS AND METHODS The study included 1253 patients on hemodialysis. IL13, IL4R, IL18, IL12A, IL12B, IL28B, MCP1, GC, VDR, and RXRA gene polymorphisms were tested. The… CONTINUE READING

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