T-helper-2 cytokine responses to Sj97 predict resistance to reinfection with Schistosoma japonicum.

@article{Leenstra2006Thelper2CR,
  title={T-helper-2 cytokine responses to Sj97 predict resistance to reinfection with Schistosoma japonicum.},
  author={Tjalling Leenstra and Luz P. Acosta and Haiwei Wu and Gretchen C. Langdon and Julie S. Solomon and Daria Llenaresas Manalo and Li Su and Mario A. Jiz and Blanca R. Jarilla and Archie O. Pablo and S T McGarvey and Remigio M. Olveda and Jennifer F. Friedman and Jonathan D. Kurtis},
  journal={Infection and immunity},
  year={2006},
  volume={74 1},
  pages={370-81}
}
Although schistosomiasis is effectively treated with Praziquantel, rapid reinfection with rebound morbidity precludes effective control based on chemotherapy alone and justifies current efforts to develop vaccines for these parasites. Using a longitudinal treatment-reinfection study design with 616 participants 7 to 30 years of age, we evaluated the relationship between cytokine responses to Schistosoma japonicum soluble adult worm extract (SWAP), Sj97, Sj22.6, and Sj67, measured 4 weeks after… CONTINUE READING
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