T-cryptantigen exposure in neonatal necrotizing enterocolitis.

  title={T-cryptantigen exposure in neonatal necrotizing enterocolitis.},
  author={Robert L Klein and Robert W. Novak and Pavel Nov{\'a}k},
  journal={Journal of pediatric surgery},
  volume={21 12},
Sixty-two infants with necrotizing enterocolitis were prospectively evaluated for evidence of the Thomson-Friedenreich cryptantigen (TCA) on their red cell surfaces. The TCA is exposed when bacterially derived neuraminidase acts on the surface of the red cells, cleaving off the N-acetylneuraminic acid, which hides the antigen. Seventeen patients (27%) had red cell TCA exposure as demonstrated by agglutination of their red cells by peanut lectin. This test is a simple agglutination procedure… CONTINUE READING


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