T cells and natural killer cells after treatment of hairy cell leukaemia with 2-chlorodeoxyadenosine.

@article{Schirmer1997TCA,
  title={T cells and natural killer cells after treatment of hairy cell leukaemia with 2-chlorodeoxyadenosine.},
  author={Michael Schirmer and Wolfgang Hilbe and Françoise Geisen and Josef Thaler and Guenther Konwalinka},
  journal={Acta haematologica},
  year={1997},
  volume={97 3},
  pages={180-3}
}
We report that continuous suppression of CD4+ lymphocyte subsets does not necessarily lead to an increased rate of infections more than 6 months after treatment of hairy cell leukemia (HCL) with 2-chlorodeoxyadenosine (cladribine; 2-CdA). In a retrospective analysis of 17 consecutive patients with HCL treated with 2-CdA and followed thereafter for an average of 440 days (ranging from 71 to 1,046 days), all lymphocyte subsets significantly decreased after therapy. However, natural killer (NK… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…