T cell vaccination in systemic lupus erythematosus with autologous activated T cells.

@article{Li2005TCV,
  title={T cell vaccination in systemic lupus erythematosus with autologous activated T cells.},
  author={Zhan-guo Li and Rong Mu and Zhi-Jun Dai and X M Gao},
  journal={Lupus},
  year={2005},
  volume={14 11},
  pages={884-9}
}
Systemic lupus erythematosus (SLE) is an autoreactive T cell mediated autoimmune disease. Immunization with inactivated autoreactive T cells may induce idiotype anti-idiotypic reaction to deplete specific subsets of autoreactive T cells involved in SLE. Six SLE patients unsuitable or refused to use immunosuppressants were treated with T cell vaccination. Their clinical manifestations and laboratory parameters including mixed lymphocyte reactions were evaluated. Autoreactive T cell clones were… CONTINUE READING
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