T-cell tolerance to the developing equine conceptus.

  title={T-cell tolerance to the developing equine conceptus.},
  author={Douglas F Antczak},
  journal={Reproduction in domestic animals = Zuchthygiene},
  volume={47 Suppl 4},
One of the most intriguing and dramatic examples of immunological tolerance is displayed by the mammalian foetal-placental unit, which thrives as a semi-allograft in the mother's uterus during pregnancy. The success of the so-called foetal allograft stands in stark contrast to the failure of most tissue and organ grafts to survive without genetic matching of donor and recipient or drastic immunosuppression of the recipient's immune system. Experiments conducted over the past 60 years have… CONTINUE READING