T-cell regulation by CD4 regulatory T cells during hepatitis B and C virus infections: facts and controversies.

@article{Manigold2007TcellRB,
  title={T-cell regulation by CD4 regulatory T cells during hepatitis B and C virus infections: facts and controversies.},
  author={Tob{\'i}as Manigold and Vito Racanelli},
  journal={The Lancet. Infectious diseases},
  year={2007},
  volume={7 12},
  pages={
          804-13
        }
}
In the past few years, we have witnessed extraordinary advances in the understanding of the functions of regulatory T (Treg) cells in immunity against pathogens. However, controversy exists over the part that these cells play in determining the outcome of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, the two main causes of chronic liver inflammation worldwide. Treg-cell responses may be either beneficial or detrimental to those infected with HBV and HCV, by either limiting… CONTINUE READING
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