T cell receptor Vbeta repertoire of T lymphocytes and T regulatory cells by flow cytometric analysis in healthy children.

@article{McleanTooke2008TCR,
  title={T cell receptor Vbeta repertoire of T lymphocytes and T regulatory cells by flow cytometric analysis in healthy children.},
  author={Andrew P. C. Mclean-Tooke and Dawn Barge and Gavin P Spickett and Andrew R Gennery},
  journal={Clinical and experimental immunology},
  year={2008},
  volume={151 1},
  pages={190-8}
}
Evaluation of the T cell receptor (TCR) Vbeta repertoire by flow cytometric analysis has been used for studying the T cell compartments for diseases in which T cells are implicated in the pathogenesis. For the interpretation of these studies information is needed about Vbeta usage in healthy individuals and there are few data for normal usage in paediatric populations. We examined the T lymphocyte (sub)populations in 47 healthy controls (age range: 3 months-16 years). We found non-random Vbeta… CONTINUE READING

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