T cell receptor V alpha gene segment with alternate splicing in the junctional region.

@article{Marche1993TCR,
  title={T cell receptor V alpha gene segment with alternate splicing in the junctional region.},
  author={Patrice N Marche and Adrien Six and H Gah{\'e}ry and Carine Gris-Liebe and Pierre Andr{\'e} Cazenave and Evelyne Jouvin-Marche},
  journal={Journal of immunology},
  year={1993},
  volume={151 10},
  pages={5319-27}
}
The locus encoding mouse TCR-alpha chain includes approximately 100 V alpha gene segments that can be organized in about 20 structural subfamilies. Southern blot analysis of a T cell line derived from the BALB/c strain, M5T, has indicated that both alpha loci were rearranged, as assessed by the deletion of the delta locus, and that the V alpha gene segment involved in one of the rearrangements did not belong to any of the V alpha subfamilies already described. Transcripts of TCR-alpha chains… CONTINUE READING