T-cell phenotypes in mixed leukocyte reactions and after bone marrow transplantation: are Ia-antigen on T-cells a marker for GvH reactions?

Abstract

Bone marrow transplantation (BMT) offers an alternative in the treatment of lethal blood disorders. Cells of the restored lymphoid System are then of donor origin. There is a high incidence of lethal infections (approx. 25%) during the first 4 months following BMT, presumably due to a pronounced cellular and humoral immunological deficiency [6, 161. Graft… (More)

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