T-cell lymphoblastic leukemia/lymphoma in Nijmegen breakage syndrome.

  title={T-cell lymphoblastic leukemia/lymphoma in Nijmegen breakage syndrome.},
  author={Srdjan S Pasi{\'c} and Dragana Vuji{\'c} and Maurilia Fiorini and Lucia Dora Notarangelo},
  volume={89 8},
Nijmegen breakage syndrome (NBS) is a rare autosomal-recessive disorder characterized by microcephaly, immunodeficiency and predisposition to cancer, mainly B-cell lymphomas. Our 10-years-old female patient with NBS developed T-cell lymphoblastic leukemia/lymphoma (TLBL/ALL). The use of standard chemotherapy in our patient, except for cranial irradiation, led to complete and sustained remission of TLBL/ALL. In patients with chromosomal instability syndromes chemotherapy must be modified and… CONTINUE READING
8 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…