T cell clones specific for IgG2a of the a allotype: direct evidence for presentation of endogenous antigen.

Abstract

T cell clones specific for IgG2a of the alpha allotype have been isolated from C57BL/6J mice. Antigenic determinants recognized by these clones were localized by using a panel of hybrid IgG2b-IgG2a myeloma proteins. These experiments provide evidence for two distinct antigenic sites, one located in a segment encompassing the hinge region and most of the CH2… (More)

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@article{Bikoff1986TCC, title={T cell clones specific for IgG2a of the a allotype: direct evidence for presentation of endogenous antigen.}, author={Elizabeth K. Bikoff and Barbara K. Birshtein}, journal={Journal of immunology}, year={1986}, volume={137 1}, pages={28-34} }