T-cell-based diagnosis of neonatal multidrug-resistant latent tuberculosis infection.

@article{Richeldi2007TcellbasedDO,
  title={T-cell-based diagnosis of neonatal multidrug-resistant latent tuberculosis infection.},
  author={Luca Richeldi and Katie J Ewer and Monica Losi and Barbara Maria Bergamini and Kerry A. Millington and Leonardo M Fabbri and Ajit Lalvani},
  journal={Pediatrics},
  year={2007},
  volume={119 1},
  pages={e1-5}
}
Young children exposed to tuberculosis have a high risk of progression to severe tuberculosis disease, but diagnosis of recent infection is hindered by the poor sensitivity of the tuberculin skin test. Whether new blood tests can detect latent infection in this vulnerable group is unknown because there is no gold standard. We monitored a tuberculin skin test-negative infant whose mother had infectious multidrug-resistant tuberculosis with enzyme-linked immunospot, a blood test that enumerates… CONTINUE READING