T cell abnormalities in systemic sclerosis with a focus on Th17 cells.

@article{Brembilla2012TCA,
  title={T cell abnormalities in systemic sclerosis with a focus on Th17 cells.},
  author={Nicol{\`o} Costantino Brembilla and Carlo Chizzolini},
  journal={European cytokine network},
  year={2012},
  volume={23 4},
  pages={128-39}
}
Systemic sclerosis (SSc) is a connective tissue disorder characterized by vascular alterations and deregulated fibroblast activation leading to fibrosis of the skin and internal organs. SSc is thought to be an autoimmune disease, owning the presence of auto-antibodies. Genetic studies lend support to the critical role exerted by the immune response in the physiopathology of the disease, since several of the SSc-associated polymorphisms have been found in genes involved in the immune response… CONTINUE READING