T-antigen is the only detectable protein on the nucleosome-free origin region of isolated simian virus 40 minichromosomes


A nucleosome-free region or nucleosome gap, containing the origin of replication and the transcriptional promoter elements, is observed on 20%–25% of the SV40 minichromosomes isolated at physiological ionic strength at late time during the infectious cycle. We found that this subpopulation of gapped minichromosomes was more sensitive to digestion with a… (More)
DOI: 10.1007/BF00327472


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