T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice

@inproceedings{Neill2012TRC,
  title={T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice},
  author={Daniel R Neill and Vitor E Fernandes and Laura Wisby and Andrew R. Haynes and Daniela M Ferreira and Ameera Laher and Natalie R Strickland and Stephen B Gordon and Paul Denny and Aras Kadioglu and P. W. Andrew},
  booktitle={PLoS pathogens},
  year={2012}
}
Streptococcus pneumoniae is an important human pathogen responsible for a spectrum of diseases including pneumonia. Immunological and pro-inflammatory processes induced in the lung during pneumococcal infection are well documented, but little is known about the role played by immunoregulatory cells and cytokines in the control of such responses. We demonstrate considerable differences in the immunomodulatory cytokine transforming growth factor (TGF)-β between the pneumococcal pneumonia… CONTINUE READING
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