T-Cell immunodeficiency in mice receiving lectin and cyclophosphamide

  title={T-Cell immunodeficiency in mice receiving lectin and cyclophosphamide},
  author={Lev N. Fontalin and T. K. Kondrat'eva and N. V. Mikheeva},
  journal={Bulletin of Experimental Biology and Medicine},
Cyclophosphamide injections to mice following T cell mitogen (lectins from Lens culinaris and concanavalin A) were shown to suppress (20-40-fold) thymus-dependent response to SRBC. At the same time no damage-specific and polyclonal response to thymus-independent antigen and polyclonal activator of B cells--lipopolysaccharide--has been observed. Injections… CONTINUE READING