T(1)- and T(2)(*)-dominant extravasation correction in DSC-MRI: part II-predicting patient outcome after a single dose of cediranib in recurrent glioblastoma patients.

@article{Emblem2011T1AT,
  title={T(1)- and T(2)(*)-dominant extravasation correction in DSC-MRI: part II-predicting patient outcome after a single dose of cediranib in recurrent glioblastoma patients.},
  author={Kyrre Eeg Emblem and Atle Bj{\o}rnerud and Kim Mouridsen and R. J. H. Borra and Tracy T Batchelor and Rakesh K. Jain and A. G. Sorensen},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2011},
  volume={31 10},
  pages={
          2054-64
        }
}
A 'vascular normalization index' (VNI) based on the changes in the magnetic resonance imaging (MRI) parameters K(trans) and cerebral blood volume (CBV), combined with blood sampling, has been shown to correlate with patient outcome in recurrent glioblastoma after a single dose of antiangiogenic therapy. Here, by applying a novel contrast agent extravasation correction method insensitive to variations in tissue mean transit time, we show that a similar VNI parameter can be derived from a single… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 19 CITATIONS

Impact of Software Modeling on the Accuracy of Perfusion MRI in Glioma.

  • AJNR. American journal of neuroradiology
  • 2015
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

ABCD1 dysfunction alters white matter microvascular perfusion

  • Brain : a journal of neurology
  • 2017
VIEW 1 EXCERPT
CITES METHODS

PET-MR Imaging in Head and Neck.

  • Magnetic resonance imaging clinics of North America
  • 2017
VIEW 1 EXCERPT
CITES BACKGROUND