Systems pharmacology-based approach for dissecting the active ingredients and potential targets of the Chinese herbal Bufei Jianpi formula for the treatment of COPD

@inproceedings{Zhao2015SystemsPA,
  title={Systems pharmacology-based approach for dissecting the active ingredients and potential targets of the Chinese herbal Bufei Jianpi formula for the treatment of COPD},
  author={Peng Zhao and Jian-sheng Li and Ya Li and Yange Tian and Yonghua Wang and Chunli Zheng},
  booktitle={International journal of chronic obstructive pulmonary disease},
  year={2015}
}
BACKGROUND The Chinese herbal Bufei Jianpi formula (BJF) provides an effective treatment option for chronic obstructive pulmonary disease (COPD). However, the systems-level mechanism underlying the clinical effects of BJF on COPD remains unknown. METHODS In this study, a systems pharmacology model based on absorption filtering, network targeting, and systems analyses was applied specifically to clarify the active compounds and therapeutic mechanisms of BJF. Then, a rat model of cigarette… CONTINUE READING
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