Systems metabolic engineering of Corynebacterium glutamicum for production of the chemical chaperone ectoine

@inproceedings{Becker2013SystemsME,
  title={Systems metabolic engineering of Corynebacterium glutamicum for production of the chemical chaperone ectoine},
  author={Judith Bette Becker and Rudolf Sch{\"a}fer and Michael Kohlstedt and Bj{\"o}rn J Harder and Nicole S Borchert and Nadine Stoeveken and Erhard Bremer and Christoph Wittmann},
  booktitle={Microbial cell factories},
  year={2013}
}
BACKGROUND The stabilizing and function-preserving effects of ectoines have attracted considerable biotechnological interest up to industrial scale processes for their production. These rely on the release of ectoines from high-salinity-cultivated microbial producer cells upon an osmotic down-shock in rather complex processor configurations. There is growing interest in uncoupling the production of ectoines from the typical conditions required for their synthesis, and instead design strains… CONTINUE READING
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Systems Level Engineering of Corynebacterium glutamicum - Reprogramming Translational Efficiency for Superior Production

  • J Becker, N Buschke, R Bücker, C Wittmann
  • Eng Life Sci
  • 2010
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