Systems integration of innate and adaptive immunity.

Abstract

The pathogens causing AIDS, malaria, and tuberculosis have proven too complex to be overcome by classical approaches to vaccination. The complexities of human immunology and pathogen-induced modulation of the immune system mandate new approaches to vaccine discovery and design. A new field, systems vaccinology, weds holistic analysis of innate and adaptive… (More)
DOI: 10.1016/j.vaccine.2015.05.098

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