Systems chemistry: from chemical self-replication to trisoligo-based nanoconstruction

@article{vonKiedrowski2010SystemsCF,
  title={Systems chemistry: from chemical self-replication to trisoligo-based nanoconstruction},
  author={G{\"u}nter von Kiedrowski},
  journal={Journal of Cheminformatics},
  year={2010},
  volume={2},
  pages={O1 - O1}
}
Self-replication is one of the major principles without life could not exist. The emergence of self-replicating systems on the early earth is generally believed to have taken place before the advent of instructed protein synthesis based on a complex translation machinery. Whether the origin of self-replication is identical to the origin of the hypothetical RNA world or whether it existed at an earlier stage of evolution is an open question that has stimulated chemists to search for chemical… 
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Systems chemistry: from chemical self-replication to trisoligo-based nanoconstruction
TLDR
This lecture will introduce chemical self-replication and multicomponent assembly as facets of systems chemistry - a nascent field which understands itself as the bottom-up pendant of systems biology towards synthetic biology and goes beyond traditional prebiotic chemistry in its mission towards a quantititive dynamic understanding of complex reaction networks with autocatalytic components.

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Systems chemistry: from chemical self-replication to trisoligo-based nanoconstruction
TLDR
This lecture will introduce chemical self-replication and multicomponent assembly as facets of systems chemistry - a nascent field which understands itself as the bottom-up pendant of systems biology towards synthetic biology and goes beyond traditional prebiotic chemistry in its mission towards a quantititive dynamic understanding of complex reaction networks with autocatalytic components.
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Correspondence: kiedro@rub.de Lehrstuhl für Organische Chemie I -Bioorganische Chemie, Ruhr-Universität, Universitätsstrasse 150, 44780 Bochum
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