Systems biology of symmetry breaking during neuronal polarity formation

@article{Inagaki2011SystemsBO,
  title={Systems biology of symmetry breaking during neuronal polarity formation},
  author={N. Inagaki and Michinori Toriyama and Y. Sakumura},
  journal={Developmental Neurobiology},
  year={2011},
  volume={71}
}
Polarization, in which a single axon and multiple dendrites are formed, is crucial for neuronal functions, and symmetry breaking is the initial step of this process. Accumulating studies have revealed a number of molecules that act asymmetrically in neurons, and thereby regulate neuronal polarity. Thus, one of the major goals of current research is to understand how asymmetric signals are generated during the symmetry‐breaking step. Current models of neuronal symmetry breaking generally involve… Expand
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  • Computer Science, Mathematics
  • Symmetry
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  • 20
  • PDF
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  • 24
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  • 45
  • PDF
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  • 29
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2
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4
...

References

SHOWING 1-10 OF 48 REFERENCES
Robust Neuronal Symmetry Breaking by Ras-Triggered Local Positive Feedback
  • 104
  • PDF
Establishment of axon-dendrite polarity in developing neurons.
  • 449
The origin of neuronal polarization: a model of axon formation.
  • 49
A diffusion-based neurite length-sensing mechanism involved in neuronal symmetry breaking
  • 68
  • PDF
Neuronal Polarity and Trafficking
  • 292
PIP3 is involved in neuronal polarization and axon formation
  • 219
  • Highly Influential
Differentiated neurons retain the capacity to generate axons from dendrites
  • 92
...
1
2
3
4
5
...