Systems biology of apoptosis signaling networks.

Abstract

Apoptosis is a complex but highly defined cellular program of cell demolition. Apoptosis can be triggered by the extrinsic or the intrinsic death pathways. Deregulation of apoptosis leads to a number of serious diseases, including cancer. A substantial progress in understanding apoptotic signaling networks has been recently achieved using systems biology… (More)
DOI: 10.1016/j.copbio.2010.07.001

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