Systems biology of JAK/STAT signalling.


Signalling in multicellular organisms is mediated by complex networks that integrate extracellular and intracellular signals to generate appropriate responses regulating cell proliferation, differentiation and survival. Downstream of many cytokine and growth hormone receptors, receptor-associated JAKs (Janus kinases) activate transcription factors of the… (More)
DOI: 10.1042/BSE0450109


Cite this paper

@article{Pfeifer2008SystemsBO, title={Systems biology of JAK/STAT signalling.}, author={Andrea C. Pfeifer and Jens Timmer and Ursula Klingm{\"u}ller}, journal={Essays in biochemistry}, year={2008}, volume={45}, pages={109-20} }