Systems biology: Metabonomics

@article{Nicholson2008SystemsBM,
  title={Systems biology: Metabonomics},
  author={J. Nicholson and J. Lindon},
  journal={Nature},
  year={2008},
  volume={455},
  pages={1054-1056}
}
  • J. Nicholson, J. Lindon
  • Published 2008
  • Medicine, Biology
  • Nature
  • Organisms often respond in complex and unpredictable ways to stimuli that cause disease or injury. By measuring and mathematically modelling changes in the levels of products of metabolism found in biological fluids and tissues, metabonomics offers fresh insight into the effects of diet, drugs and disease. 
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    References

    SHOWING 1-10 OF 30 REFERENCES
    Metabolic Phenotyping in Health and Disease
    • 523
    Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism
    • 882
    Analytical strategies in metabonomics.
    • 461
    Application of metabonomics in drug development.
    • 51
    Chemometrics in metabonomics.
    • 1,026
    • PDF
    A Metabonomic Study on the Biochemical Effects of Doxorubicin in Rats Using 1H-NMR Spectroscopy
    • 37
    MetaboAnalyst: a web server for metabolomic data analysis and interpretation
    • 1,101
    • PDF