Systems biology: Metabonomics

  title={Systems biology: Metabonomics},
  author={J. Nicholson and J. Lindon},
  • J. Nicholson, J. Lindon
  • Published 2008
  • Medicine, Biology
  • Nature
  • Organisms often respond in complex and unpredictable ways to stimuli that cause disease or injury. By measuring and mathematically modelling changes in the levels of products of metabolism found in biological fluids and tissues, metabonomics offers fresh insight into the effects of diet, drugs and disease. 
    1,325 Citations

    Paper Mentions

    Observational Clinical Trial
    The purpose of the study is to compare the concentrations of Vitamin B1 (thiamine), Vitamin B6 (pyridoxal-5-phosphate), folate, Vitamin B12 (cobalamin), Vitamin C (ascorbic acid… Expand
    ConditionsAlzheimers Disease, Mild Cognitive Impairment
    Metabonomics and systems biology.
    • 6
    Metabonomics-based omics study and atherosclerosis
    • 15
    Systems Biology of Human Atherosclerosis
    • 23
    An Emerging Role for Metabolomics in Nutrition Science
    • 59
    Metabolomics: Definitions and Significance in Systems Biology.
    • 22


    Metabolic Phenotyping in Health and Disease
    • 523
    Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism
    • 882
    Analytical strategies in metabonomics.
    • 461
    Application of metabonomics in drug development.
    • 51
    Chemometrics in metabonomics.
    • 1,026
    • PDF
    A Metabonomic Study on the Biochemical Effects of Doxorubicin in Rats Using 1H-NMR Spectroscopy
    • 37
    MetaboAnalyst: a web server for metabolomic data analysis and interpretation
    • 1,101
    • PDF