Systems biological approach on neurological disorders: a novel molecular connectivity to aging and psychiatric diseases

@inproceedings{Ahmed2010SystemsBA,
  title={Systems biological approach on neurological disorders: a novel molecular connectivity to aging and psychiatric diseases},
  author={Shiek S. S. J. Ahmed and Abdul R. Ahameethunisa and Winkins Santosh and Srinivasa Chakravarthy and Suresh Kumar},
  booktitle={BMC Systems Biology},
  year={2010}
}
Systems biological approach of molecular connectivity map has reached to a great interest to understand the gene functional similarities between the diseases. In this study, we developed a computational framework to build molecular connectivity maps by integrating mutated and differentially expressed genes of neurological and psychiatric diseases to determine its relationship with aging. The systematic large-scale analyses of 124 human diseases create three classes of molecular connectivity… CONTINUE READING
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