Systems approaches to identifying gene regulatory networks in plants.

  title={Systems approaches to identifying gene regulatory networks in plants.},
  author={Terri A Long and Siobhan M. Brady and Philip N. Benfey},
  journal={Annual review of cell and developmental biology},
Complex gene regulatory networks are composed of genes, noncoding RNAs, proteins, metabolites, and signaling components. The availability of genome-wide mutagenesis libraries; large-scale transcriptome, proteome, and metabalome data sets; and new high-throughput methods that uncover protein interactions underscores the need for mathematical modeling techniques that better enable scientists to synthesize these large amounts of information and to understand the properties of these biological… CONTINUE READING