Systems Pharmacology Dissection of the Integrated Treatment for Cardiovascular and Gastrointestinal Disorders by Traditional Chinese Medicine

  title={Systems Pharmacology Dissection of the Integrated Treatment for Cardiovascular and Gastrointestinal Disorders by Traditional Chinese Medicine},
  author={Wenjuan Zhang and Qin Tao and Zihu Guo and Yingxue Fu and Xuetong Chen and Piar Ali Shar and Mohamed Shahen and Jinglin Zhu and Jun Xue and Yaofei Bai and Ziyin Wu and Zhen-zhong Wang and Wei Xiao and Yonghua Wang},
  journal={Scientific Reports},
Though cardiovascular diseases (CVDs) and gastrointestinal disorders (GIDs) are different diseases associated with different organs, they are highly correlated clinically. [] Key Method Firstly, we identified pairs of genes that are associated with CVDs and GIDs and found that these genes are functionally related. Then, the association between 115 heart meridian (HM) herbs and 163 stomach meridian (SM) herbs and their combination application in Chinese patent medicine was investigated, implying that both…
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