Systems Level Dissection of Candida Recognition by Dectins: A Matter of Fungal Morphology and Site of Infection

@inproceedings{Rizzetto2015SystemsLD,
  title={Systems Level Dissection of Candida Recognition by Dectins: A Matter of Fungal Morphology and Site of Infection},
  author={Lisa Rizzetto and Tobias Weil and Duccio Cavalieri and Sarah L Gaffen},
  booktitle={Pathogens},
  year={2015}
}
Candida albicans is an ubiquitous fungal commensal of human skin and mucosal surfaces, and at the same time a major life-threatening human fungal pathogen in immunocompromised individuals. Host defense mechanisms rely on the capacity of professional phagocytes to recognize Candida cell wall antigens. During the past decade, the host immune response to Candida was dissected in depth, highlighting the essential role of C-type lectin receptors, especially regarding the power of the Dectins' family… CONTINUE READING
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