Systemically and locally administered growth hormone stimulates bone healing in combination with osteopromotive membranes: an experimental study in rats.

@article{Hedner1996SystemicallyAL,
  title={Systemically and locally administered growth hormone stimulates bone healing in combination with osteopromotive membranes: an experimental study in rats.},
  author={Erik Hedner and A. W. van de Linde and Anders N. Nilsson},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1996},
  volume={11 12},
  pages={1952-60}
}
Growth hormone (GH) is known to be of a major importance for longitudinal bone growth, but its local effects on osteogenesis and, thus, regeneration of bone defects are less known. The aim of this investigation was to study whether GH, systemically or locally administered, has any stimulatory effects on local osteogenesis, utilizing standardized, membrane-covered, transosseous defects (5 mm diameter) in mandibles of adult albino rats. The study also addressed the question of whether GH might be… CONTINUE READING