Systemic virus distribution and host responses in brain and intestine of chickens infected with low pathogenic or high pathogenic avian influenza virus

@inproceedings{Post2011SystemicVD,
  title={Systemic virus distribution and host responses in brain and intestine of chickens infected with low pathogenic or high pathogenic avian influenza virus},
  author={Jacob Post and David W. Burt and Jan B.W.J. Cornelissen and Venice Broks and Diana J van Zoelen and Ben Peeters and J. M. J. Rebel},
  booktitle={Virology Journal},
  year={2011}
}
Avian influenza virus (AIV) is classified into two pathotypes, low pathogenic (LP) and high pathogenic (HP), based on virulence in chickens. Differences in pathogenicity between HPAIV and LPAIV might eventually be related to specific characteristics of strains, tissue tropism and host responses. To study differences in disease development between HPAIV and LPAIV, we examined the first appearance and eventual load of viral RNA in multiple organs as well as host responses in brain and intestine… CONTINUE READING
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