Systemic uptake of buprenorphine by cats after oral mucosal administration.

  title={Systemic uptake of buprenorphine by cats after oral mucosal administration.},
  author={Sheilah Ann Robertson and Patricia M. Taylor and John William Sear},
  journal={The Veterinary record},
  volume={152 22},
The plasma concentration of buprenorphine was measured by radioimmunoassay in six female cats after the administration of 0.01 mg/kg (0.033 ml/kg) buprenorphine hydrochloride solution into the side of the cat's mouth. Blood samples were taken through a preplaced jugular catheter before and one, two, four, six, 10, 15, 30, 45 and 60 minutes, and two, four, six, 12 and 24 hours after the dose was administered. The buprenorphine was accepted well by all the cats and did not cause salivation or… CONTINUE READING

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