Systemic transplantation of human adipose-derived stem cells stimulates bone repair by promoting osteoblast and osteoclast function

@inproceedings{Lee2011SystemicTO,
  title={Systemic transplantation of human adipose-derived stem cells stimulates bone repair by promoting osteoblast and osteoclast function},
  author={Kyunghee Lee and Hyunsoo Kim and Jin-Man Kim and J W Kim and Keuk-Jun Kim and Yong-Jin Kim and Se-Il Park and Jae-Ho Jeong and Young-Mi Moon and Hyun-Sook Lim and Dong-Won Bae and Joseph Sang-II Kwon and Chang-Yong Ko and Han-Sung Kim and H I Shin and Daewon Jeong},
  booktitle={Journal of cellular and molecular medicine},
  year={2011}
}
Systemic transplantation of adipose-derived stem cells (ASCs) is emerging as a novel therapeutic option for functional recovery of diverse damaged tissues. This study investigated the effects of systemic transplantation of human ASCs (hASCs) on bone repair. We found that hASCs secrete various bone cell-activating factors, including hepatocyte growth factor and extracellular matrix proteins. Systemic transplantation of hASCs into ovariectomized mice induced an increased number of both… CONTINUE READING
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