Systemic therapy for hepatocellular carcinoma: the issue of treatment stage migration and registration of progression using the BCLC-refined RECIST.

@article{Reig2014SystemicTF,
  title={Systemic therapy for hepatocellular carcinoma: the issue of treatment stage migration and registration of progression using the BCLC-refined RECIST.},
  author={Mar{\'i}a Reig and Anna Darnell and Alejandro Forner and Jordi Rimola and Carmen Ayuso and Jordi Bruix},
  journal={Seminars in liver disease},
  year={2014},
  volume={34 4},
  pages={
          444-55
        }
}
Recent advancements have improved the management of patients with liver cancer. Results of studies have informed how to stage and decide the optimal treatment option for each patient with an adequate balance between risks and benefits. The Barcelona Clinic Liver Cancer (BCLC) staging and treatment strategy has been widely endorsed for this purpose. This is not a rigid system: One of the key aspects in the management of patients is the optimal timing for systemic treatment initiation and for… CONTINUE READING
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