Systemic sclerosis-associated interstitial lung disease-proposed recommendations for future randomized clinical trials.

@article{Khanna2010SystemicSI,
  title={Systemic sclerosis-associated interstitial lung disease-proposed recommendations for future randomized clinical trials.},
  author={Dinesh Khanna and Kevin K. Brown and Philip J. Clements and Robert M. Elashoff and Daniel e. Furst and Jonathan G. Goldin and James R. Seibold and Richard M. Silver and Donald P Tashkin and Athol U Wells},
  journal={Clinical and experimental rheumatology},
  year={2010},
  volume={28 2 Suppl 58},
  pages={S55-62}
}
Pulmonary disease is the leading cause of morbidity and mortality in patients with systemic sclerosis (SSc). Recent well-designed trials in SSc-associated interstitial lung disease (SSc-ILD) have provided important insights regarding outcome measures and trial design. Recent investigations into the pathogenesis of SSc-ILD have led to a renewed interest in assessing targeted therapies in SSc-ILD. With this in mind, we propose recommendations for the design of future SSc-ILD studies in this… CONTINUE READING

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