Systemic sclerosis and bilateral lung transplantation: a single centre experience.

  title={Systemic sclerosis and bilateral lung transplantation: a single centre experience.},
  author={Rajan Saggar and Divya Khanna and Daniel e. Furst and John A Belperio and Grace S. Park and Stephen S. Weigt and Bernie M Kubak and Abbas A Ardehali and Ariss Derhovanessian and Philip J. Clements and Stan Shapiro and Chris Hunter and Aric L Gregson and Mike C Fishbein and Joseph P Lynch and David J. Ross},
  journal={The European respiratory journal},
  volume={36 4},
Lung involvement is the leading cause of death in systemic sclerosis (SSc), but lung transplantation (LT) for systemic disease remains controversial. Our objective was to comprehensively evaluate post-LT outcomes for SSc compared to idiopathic pulmonary fibrosis (IPF). We retrospectively evaluated bilateral LT recipients (LTRs) with SSc or IPF at our centre between January 1, 2003 and December 31, 2007. The primary end-point was all-cause mortality at 1 yr post-LT. Secondary end-points included… CONTINUE READING