Systemic sclerosis: New evidence re-enforces the role of B cells.


Systemic sclerosis (SSc) is characterized by widespread fibrosis, microangiopathy (vasospasms and stenosis), and formation of autoantibodies. T cell activation has been shown to contribute to fibrosis and microvasculopathy in SSc. However, recent evidence suggests that B cells are also likely to contribute in the pathogenesis of the disease. B cells are… (More)
DOI: 10.1016/j.autrev.2015.10.005


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