Systemic rapamycin without loading dose for restenosis prevention after coronary bare metal stent implantation.

@article{Stojkovic2010SystemicRW,
  title={Systemic rapamycin without loading dose for restenosis prevention after coronary bare metal stent implantation.},
  author={Sinisa M. Stojkovic and Miodrag {\vC}. Ostoji{\'c} and Milan A. Nedeljkovic and Goran Stankovi{\'c} and Branko Beleslin and V. Vukcevic and Dejan Orli{\'c} and Aleksandra Arandjelovi{\'c} and Jelena T Kosti{\'c} and Miodrag Diki{\'c} and Miloje Tomasevic},
  journal={Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions},
  year={2010},
  volume={75 3},
  pages={317-25}
}
OBJECTIVES The aim of this study was to assess the role of short oral administration of rapamycin, without loading dose, in the reduction of restenosis rate after bare metal stent implantation. BACKGROUND Previous studies suggest that the administration of oral rapamycin reduces angiographic restenosis after bare metal stent implantation. METHODS This was prospective, open-label study of 80 patients randomized to either oral rapamycin (2 mg/day for 30 days, starting within 24 hr of stent… CONTINUE READING