Systemic omega-6 essential fatty acid treatment and pge1 tear content in Sjögren's syndrome patients.

@article{Aragona2005SystemicOE,
  title={Systemic omega-6 essential fatty acid treatment and pge1 tear content in Sj{\"o}gren's syndrome patients.},
  author={Pasquale Aragona and Claudio Bucolo and Rosaria Spinella and Sebastiano Giuffrida and Giuseppe Ferreri},
  journal={Investigative ophthalmology & visual science},
  year={2005},
  volume={46 12},
  pages={4474-9}
}
PURPOSE To determine the effect of oral omega-6 essential fatty acids on PGE(1) tear content and signs and symptoms of ocular discomfort in patients with Sjögren's syndrome (SS). METHODS This randomized, double-masked, controlled, clinical trial involved 40 patients with primary SS, divided into two groups: group 1: 20 patients (18 women, 2 men; mean age, 36.9 +/- 7.9 years [SD]) treated for 1 month with linoleic acid (LA; 112 mg), and gamma-linolenic acid (GLA; 15 mg) administered twice… CONTINUE READING
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