Systemic markers of the redox balance in chronic obstructive pulmonary disease.

  title={Systemic markers of the redox balance in chronic obstructive pulmonary disease.},
  author={M. Soledade C. S. Santos and Amanda Lima Oliveira and Ana Maria Viegas-Crespo and L{\'a}zaro Vicente and Ana Paula Barreiros and Pedro Valadas Monteiro and Teresa Pinheiro and Ant{\'o}nio Bugalho de Almeida},
  journal={Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals},
  volume={9 6},
Chronic obstructive pulmonary disease (COPD) is highly prevalent and its pathogenesis is still not completely clarified. Clinically stable patients (n=21) and healthy subjects (n=24) were studied for blood markers of oxidative injury and antioxidant status. The plasma concentration of protein carbonyls was significantly increased in COPD patients, both ex-smokers (0.76 +/- 0.28 nmol mg(-1)) and smokers (0.99 +/- 020 nmol mg(-1)) versus controls (0.49 +/- 0.14 nmol mg(-1)) . The concentration of… CONTINUE READING
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